Are physiological oscillations physiological?

L Xiong, A Garfinkel - The Journal of Physiology, 2023 - Wiley Online Library
… sinoatrial node (SAN), the heart’s natural pacemaker, there are at least two oscillatory … ,
generating rhythmic pacemaking.’ Whether the origin of the cellular oscillation is subcellular or …

[HTML][HTML] The cardiac pacemaker story—fundamental role of the Na+/Ca2+ exchanger in spontaneous automaticity

Z Kohajda, A Loewe, N Tóth, A Varró… - Frontiers in …, 2020 - frontiersin.org
… Few areas of cardiac cellular electrophysiology had more intense debate over the years …
In the last two decades, we could witness the struggle of two competing oscillator concepts …

Pacemaking in cardiac tissue. From IK2 to a coupled‐clock system

E Carmeliet - Physiological Reports, 2019 - Wiley Online Library
… (2010) in “Competing oscillators in cardiac pacemaking”: “… 2016), I mentioned some personal
historical notes. Afterwards, … a more substantial review on the historical evolution of cardiac

Biological Pacemakers: Present and Future

T Mesquita, R Miguel-dos-Santos… - Circulation Research, 2024 - Am Heart Assoc
… of SAN pacemaker cells relies on the activity of dual oscillators to … Over the past 2 decades,
efforts in creating biological pacemakers have been … Please describe the competing interests …

Pacemaker Channels and the Chronotropic Response in Health and Disease

K Hennis, C Piantoni, M Biel, S Fenske… - Circulation …, 2024 - Am Heart Assoc
… , there are 2 competing right atrial pacemakers located near the … In fact, during the past 20+
years, different research groups … firing SAN pacemaker cells, that is, voltage oscillators of the …

Implementing Biological Pacemakers: Design Criteria for Successful Transition From Concept to Clinic

ER Komosa, DW Wolfson, M Bressan… - Circulation …, 2021 - Am Heart Assoc
pacemakers have been published over the past 2 decades, however, clinical implementation
has yet to be realized. Here, we consider biological pacemakers in the contextoscillation. …

Robust neuromorphic coupled oscillators for adaptive pacemakers

R Krause, JJA van Bavel, C Wu, MA Vos, A Nogaret… - Scientific Reports, 2021 - nature.com
… We implement an adaptive cardiac pacemaker model and validate our results with … context
of a promising future application. Our pacemaker model consists of three coupled oscillators

Principles, mechanisms and functions of entrainment in biological oscillators

A Jiménez, Y Lu, A Jambhekar… - Interface Focus, 2022 - royalsocietypublishing.org
… Isolated individual sinoatrial node cardiac pacemaker cells have varying periods [66–69],
but at high density, they exhibit the stereotypical 80 beats per minute [61,70]. Dispersed …

The Bionic Pacemaker

GM Drzewiecki - … Engineering Principles Of The Bionic Man, 2023 - books.google.com
… The history of the bionic cardiac pacemaker will be reviewed … cellular oscillators or auto-arrhythmic
cells, focusing on the cardiac … when the two pacemakers compete with each other in a …

Advances in controller design of pacemakers for pacing control: A comprehensive review

R Dey, N Dey, RS Dhar, U Mondal… - Annual Reviews in …, 2024 - Elsevier
review focusing on the modeling of artificial pacemakers and the … oscillator with a cubic term
is used to model the cardiac … In past years the nonlinear dynamics of heart has been studied …